What Is OralDNA Testing?
OralDNA testing is a powerful diagnostic test that uses saliva testing to analyze your oral bacteria, gene markers, and specific pathogens. Much like bloodwork at your annual physical, this salivary diagnostic testing gives us a deeper look at what’s happening below the surface.
Through a simple saliva sample—collected using a saline solution rinse and a funneled collection tube—you can enter saliva in just minutes. This non-invasive sample collection is comfortable and quick. The saliva sample is then sent to OralDNA Labs for detailed analysis.
The result? A comprehensive, easy-to-understand report that identifies:
- Specific bacteria linked to periodontal disease and tooth decay
- Harmful oral pathogens contributing to gum inflammation
- Genetic markers related to chronic inflammation
- Genetic risk factors for gum disease and systemic diseases
- Viral and fungal organisms such as HPV, HSV, and Candida
The graphic presentation of the test results provides a clear bacterial profile and clinical information that helps us personalize your treatment plan with precision.
Why Does OralDNA Matter for Overall Health?
Emerging research shows strong connections between oral bacteria and systemic inflammation, which may contribute to cardiovascular disease, birth complications, and other chronic medical conditions. Certain oral pathogens can enter the bloodstream and affect overall health.
With OralDNA diagnostic testing, we can detect high levels of specific pathogens, bacteria, and more before they cause irreversible damage. Early detection allows us to intervene sooner, reducing your risk of long-term or more serious health issues.
What Can OralDNA Testing Detect?
With OralDNA Labs®, we offer several types of OralDNA diagnostic tests tailored to your needs:
MyPerioPath® – Periodontal Disease Testing
This test detects 11 harmful bacteria known to cause gum disease and threaten both oral and systemic health. If you’ve noticed bleeding gums (that “pink in the sink” moment), gum inflammation, or persistent bad breath, this diagnostic testing can uncover the specific bacteria responsible.
Identifying the types of bacteria present allows us to customize your periodontal treatment plan rather than relying on a one-size-fits-all approach.
MyPerioID® – Genetic Risk Assessment
Some patients are genetically predisposed to severe gum inflammation and periodontal disease. MyPerioID® analyzes gene markers—specifically related to IL-6—to determine your genetic risk.
If you carry certain genetic markers, you may have a stronger inflammatory response to oral infections. Understanding your genetic makeup helps us create preventive strategies to protect your good oral health long-term.
OraRisk® Caries – Cavity Risk Testing
Tooth decay is incredibly common—affecting 90% of U.S. adults. But cavities aren’t just about sugar; they’re caused by specific bacteria that produce acid.
This oral dna testing identifies three major bacteria responsible for tooth decay. By understanding your bacterial profile, we can design a preventive treatment plan that supports good oral hygiene and lowers your risk factor for future cavities.
OraRisk® HPV and HSV
These tests detect viruses linked to oral cancer and oropharyngeal infections. Early detection of high-risk strains can be life-changing. Our conservative, patient-centered approach means we prioritize proactive screening when clinical considerations suggest testing is appropriate.
OraRisk® Candida
Candida is a fungal infection that can affect anyone, especially those with diabetes, autoimmune conditions, dentures, or compromised immune systems. Candida overgrowth may signal underlying chronic medical conditions or systemic diseases.
This salivary testing identifies up to 9 Candida species, allowing us to recommend targeted antifungal treatment when needed.
Celsus One™ – Inflammatory Response Testing
This advanced DNA testing evaluates eight gene markers related to your body’s inflammatory response. For patients with chronic inflammation or systemic health concerns, this diagnostic test offers valuable insight into how your body reacts to oral bacteria and infections.
How OralDNA Improves Your Treatment Plan
At Sensational Smiles, we are committed to highly personalized care. OralDNA testing supports our collaborative, you-centered philosophy.
With your test results in hand, we can:
- Create a targeted treatment plan based on your specific bacteria
- Choose antibiotics or therapies tailored to your bacterial profile
- Monitor progress through follow-up saliva testing
- Adjust your dental services as your needs evolve
- Help reduce your risk of cardiovascular disease and other systemic health complications
The graphic representation of your results makes it easy to understand what’s happening in your mouth. We’ll review your detailed report together and answer all your questions.
Who Should Consider OralDNA Testing?
OralDNA diagnostic testing may benefit adults who:
- Have bleeding gums or gum disease
- Experience chronic bad breath
- Have recurring tooth decay
- Have dental implants and want to protect them from infection
- Struggle with poor oral hygiene
- Have chronic medical conditions
- Are at higher risk for heart disease or cardiovascular disease
- Want early detection of oral pathogens
- Have unexplained oral infections
Even patients with good oral hygiene can harbor high levels of harmful bacteria. Testing helps us identify risk factors before symptoms become severe.
What to Expect During the Testing Process
The process is simple and comfortable:
- Rinse with a saline solution.
- Enter saliva into a funneled collection tube.
- We send the saliva sample to the lab.
- Receive your comprehensive test results.
There are no needles, no discomfort, and no downtime. The entire sample collection takes just minutes during your general dentistry appointment.
Frequently Asked Questions About OralDNA
Is OralDNA testing painful?
No. The test involves saliva testing using a saline rinse and a funneled collection tube. It is completely non-invasive.
How long does it take to get test results?
Results typically return within a couple of weeks. We will review your detailed report and graphic presentation of the test results with you.
Does insurance cover OralDNA diagnostic testing?
Coverage varies. Our team can help you understand your benefits and any out-of-pocket costs.
Can OralDNA detect oral cancer?
While it does not diagnose cancer directly, certain tests detect HPV strains associated with oral cancer risk, supporting early detection.
How often should I be tested?
Depending on your risk factor and clinical information, we may recommend periodic re-testing to monitor bacterial levels and treatment progress.
Can OralDNA help with bad breath?
Yes. Chronic bad breath is often linked to specific bacteria. Identifying and treating those oral pathogens can significantly improve breath and overall oral hygiene.
A Proactive Approach to Good Oral Health
Since 1958, Sensational Smiles has been a trusted destination for advanced, compassionate dental care in Fairfax. Led by Dr. Mary-Stuart Gallian, our team takes a conservative approach that prioritizes preserving your natural teeth while embracing modern dental technology.
OralDNA diagnostic testing is another way we provide state-of-the-art care rooted in science, precision, and prevention. By identifying harmful bacteria, genetic risk, and systemic connections early, we can protect your smile—and your overall health—for years to come.











